Will And Grace Spin-Off With Jack And Karen? Former Will and Grace co-stars Megan Mullally and Sean Hayes are reportedly set to star in a spin-off of the hit comedy where the double-trouble duo will reprise their roles as Karen and Jack. The show is currently in development with NBC.According to sources, Hayes was keen on a spin-off soon after Will and Grace ended in 2006 – but was put off by the failure of Matt LeBlanc’s Friends spin-off Joey.Plans were then derailed when Mullally landed a talk show, but that then flopped, throwing the pair back together again.An insider tells the National Enquirer: “They feel there is still a lot of life left in their characters and a lot of comic possibilities.”If a pilot episode is successful, Karen and Jack could be on the air in the U.S. next autumn.Exciting news for Will and Grace fans. A lot of people were bummed when the show ended. And there has to be a few special cameo appearances from Will and Grace in this, right?!