Bradley Cooper loves to mix business with pleasure – after being romantically linked with his He's Just Not That Into You co-star Jennifer Aniston, the actor stepped out with latest leading lady Renee Zellweger on Tuesday night.

The pair – who star together in upcoming movie Case 39 – enjoyed a "flirty" dinner date at fancy Italian eatery Antonucci on Manhattan's Upper East Side.

"If they're just friends, they were being awfully affectionate!" a fellow diner tells OK!.

"Throughout the dinner they were playful and flirty. She played with her hair a lot, and she would often touch his arm when she was making a point about something.

"At one point, he seemed to want to whisper something to her as if it were a secret. He spoke into her ear and then they both started giggling."

Bradley is all smiles after his diner date

Less romantic was when Bradley reportedly blurted out "You [expletive]-er!" after Renee insisted on picking up the tab, and then left her struggling to get a taxi.

Three cabs drove past before Renee managed to get a ride.

Renee hails a cab in style

Bradley recently denied rumours he's dating Jennifer Aniston.

"In America, its not like it is here," he explained. "She's someone who is super, super known. Famous. If someone says 'hello' to her, it's given that he's fallen in love with her. So, no. No. She's a very, very interesting woman, but she's simply a friend."

'Interesting'? High praise, indeed. Now Jennifer just needs to return the complement by giving an interview in which she calls Brad 'different'.

Jen's men